Carole Cook as Grandma Helen
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Of the four actors who played grandparents in "Sixteen Candles," only Cook, who famously fondled Sam in one of the film's early scenes, is still living. In the late mid to late '80s, Cook, who was close friends with Lucille Ball, appeared in "Dynasty" and "Cagney & Lacey," and later, "Grey's Anatomy." She is still married to actor Tom Troupe, whom she wed in 1964.